Fillers are minimally invasive aesthetic procedures widely performed worldwide, involving the injection of needles and cannulas into different layers of the skin and subcutaneous tissue. Unlike other injection methods such as mesotherapy, youth vaccines, and PRP, the main characteristic that distinguishes fillers is their ability to provide volume to the injected area for extended periods. Fillers can be used to eliminate wrinkles, provide lifting in the treated area, which involves lifting or stretching from the surface, and create volume. 

Hyaluronic acid fillers are currently the most widely used fillers. In fact, when people think of fillers, or the only material known as filler by many, hyaluronic acid is the first thing that comes to mind. However, mineral fillers have also gained prominence in recent years. Hyaluronic acid is highly compatible with tissue because it is a fundamental component of the extracellular matrix of humans. Since it already exists in the human body, it is not expected to cause adverse effects in the tissue. If the patient is not satisfied with the results or if a possible complication occurs, there is also the chance of dissolution with a substance called hyaluronidase, either immediately or later. These dissolving agents only dissolve the filler and do not affect the person’s own hyaluronic acid. Even if hyaluronic acid fillers are not dissolved, they cannot be completely permanent and will disappear over time. They generally last between 6 to 12 months. 

Where are hyaluronic acid fillers used? 

– Increasing and shaping lip volume, correcting asymmetry 

– Providing a moist appearance to the lips in small applications 

– Providing volume in midface areas such as cheekbones, temples, nasolabial area 

– Lengthening the chin and shaping it forward 

– Eliminating chin dimples 

– Enhancing the jawline 

– Reducing hollowing under the eyes 

– Reducing prejowl sulcus and marionette lines 

– Reducing volume loss on the hands 

– Reducing acne scars, depressions, and scars 

How are hyaluronic acid fillers applied? 

Before applying to the patient, the area is thoroughly cleaned using various chemical agents, and topical anesthetics are applied to the area to provide anesthesia specifically for needle applications, and it is left on for at least 20 minutes. The filler procedure varies from region to region, but if considered as a single area, it takes about 10-15 minutes on average. 

In many parts of the face, application is performed with a blunt-tipped cannula instead of a needle. Before this application, since the cannula is not sharp, after a guide needle is used to create an entry for the cannula to pass through the skin, the filler is injected to the desired level under the skin. It is a safe and widely preferred method to preserve vascular and nerve structures and to minimize the risk of complications. 

Semi-permanent or Biostimulant (Collagen Stimulating) Fillers 

Calcium Hydroxyapatite Fillers 

In this process called biological stimulation, collagen synthesis of the person is triggered, and the response obtained day by day increases. Its effectiveness lasts up to 2 years, so it is considered semi-permanent. Second or third additional applications may be performed if deemed necessary to extend the effectiveness. These types of fillers are obtained in the laboratory and consist of a gel containing calcium hydroxyapatite and water. After injection, the gel, which serves as a carrier, is absorbed by the body, and during this process, microspheres containing calcium hydroxyapatite are released, stimulating cell activity in the area and increasing collagen production. It is preferred for hand and especially lower face applications. 

What Should Be Considered Before and After Filler Injections? 

Pain relievers, aspirin, blood thinners, green tea, ginkgo biloba, garlic, ginseng, echinacea, and other herbs should not be taken for 1 week before the procedure as they may increase the risk of bruising during the filler procedure. Massage should not be performed in the application area unless instructed by your doctor. Intensive sports, Turkish baths, saunas, and sweating are not recommended after the procedure. If pain, sensitivity, or bruising is observed outside the expected symptoms that your doctor has informed you about, we recommend consulting the performing physician.